Neurovascular coupling in the brain

The Mughal Laboratory (The Neurovascular Research Unit) studies the neurovascular coupling mechanisms involved in regulation of blood flow in the brain and clearance of metabolic by-products. Along with providing the basic understanding of these mechanisms in physiology, the research also extends to the vascular cognitive impairment and dementia (VCID) including stroke and CADASIL. By using pre-clinical models and cutting-edge imaging approaches, the Mughal laboratory provides a thorough understanding of different neurovascular mechanisms along with the contributions of different vascular compartments (arteries—capillaries— veins) with the aim to extend this knowledge from physiology to the disease models.

The research program is supported by multiple on-going projects. Students will have the option to work on any project in the lab, and to take it in new directions. 
 

Research keywords: Neurovascular, Ion channels, Calcium signaling, Blood flow in the brain