Mathieu Perez

During his undergraduate training, Mathieu specialized in studying the wound-healing structure and process of plants from the perspective of physical biochemistry. To gain insights into this field, he employed a range of analytical techniques, including NMR, EM, AFM, and GC/LC-MS. Fascinated by the interplay of chemistry, physics, and human biology, Mathieu decided to further explore the realm of protein structure and function. This led him to undertake an internship at Harvard Medical School, where he immersed himself in the disciplines of x-ray crystallography and cryo-EM. His primary focus was to investigate the structure and interactions of ubiquitin and ubiquitin-like proteins with DUBs.

Driven by an increasing interest in unraveling the fundamental principles of biology to elucidate human pathology, Mathieu subsequently joined the National Institute of Allergy and Infectious Diseases (NIAID). During his time there, he dedicated his efforts to unraveling the biomolecular processes underlying familial eosinophilia.

Mathieu's extensive and diverse research experience in chemistry and physics has endowed him with the versatility to tackle various research questions. Currently, he has embarked on a combined MD-PhD (MSTP) program at the University of California, San Francisco (UCSF), NINDS-NIH, and the Wellcome Sanger Institute, affiliated with the University of Cambridge. His studies revolve around investigating the underlying causes of specific cell vulnerability in neurodegeneration, blending his clinical and research interests.