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Pratik Koppikar
NIH Cambridge Scholar
B.S., The University of Texas at Dallas, 2023
Dr. Michael E. Ward (NINDS), Prof. Florian T. Merkle (Cambridge),
and Prof. Andrew Bassett (Cambridge)
Prime editing, Single-cell omics, Neuroscience
Pratik graduated from The University of Texas at Dallas summa cum laude, with Collegium V Honors, and as a Eugene McDermott Scholar. While an undergraduate, he worked to optimize microfluidic systems for the independent treatment of axons from soma for nociceptive involvement under the supervision of Dr. Joseph Pancrazio in the bioengineering department. In 2021, Pratik worked at PerkinElmer Genomics, now Revvity, to develop a novel primary screening assay for the lipid storage disease Cerebrotendinous Xanthomastosis. He has additionally conducted research as an undergraduate at the Yong Loo Lin School of Medicine at the National University of Singapore under Dr. Jai Polepalli, working to design a co-immunoprecipitation methodology for the quantification of the serotonin 5HT3A receptor, and at the Yale School of Medicine under Dr. Monkol Lek, where he helped develop a single-cell muscle cell atlas.
During his graduate study as an NIH Cambridge Scholar, Pratik will work to improve methods of prime editing stem cells and obtaining downstream pooled readouts. Coupling method development with single-cell transcriptome readouts, he will then investigate how individual variants affect phenotypic outcomes and disease states.