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NIH Cambridge Scholar MD/PhD
B.A. Biology, Carleton College, 2013
Medical student at University of Minnesota (In progress)
Dr. Pam Schwartzberg (NIAID),
Prof. Ken Smith (Cambridge)
and Prof. Paul Lyons (Cambridge)
Immunology, Cell signaling, Genetics
Madeline graduated with Distinction and Honors from Carleton College with a B.A. in Biology. During this time, she explored the molecular basis of sexually dimorphic coloration and behavioral traits in lizards under the supervision of Dr. Matt Rand and completed her Senior Integrative Exercise on cellular stress response in type 2 diabetes with Dr. John Tymoczko, for which she was awarded Distinction.
Long interested in medicine, she sought to gain exposure to translational research and spent three years as a post-baccalaureate IRTA fellow in the lab of Dr. Charles Venditti at the National Human Genome Research Institute. There, she studied the pathophysiology underlying methylmalonic acidemia, an inborn error of metabolism, as well as developed novel biomarkers and gene therapies for the disorder.
This time at the NIH cemented her desire to pursue a career as a physician scientist and she chose to join the University of Minnesota Medical Scientist Training Program, where she has completed her preclinical coursework at this time. Her scientific interests now focus on cellular processes and signaling within the context of immunologically-mediated disorders. As an NIH Cambridge Scholar, she will investigate the role of CD8+ T cell signatures in clinical outcomes of primary immunodeficiencies and T cell exhaustion.
Beyond the lab, she desires to use medicine and healthcare systems as tools to promote social justice, particularly within the framework of global health. She completed a NIH Academy Fellowship, focusing on health disparities in the DC area, and a Walter H. Judd International Graduate & Professional Fellowship examining pediatric infectious disease management in low-resource settings within Uganda.